Quality control of chondroitin sulphate used in dietary supplements

Isotachophoretic Determination of Glucosamine and Chondroitin Sulphate in Dietary Supplements

Václavíková E., Kvasnička F. (2013): Isotachophoretic determination of glucosamine and chondroitin sulphate in dietary supplements. Czech J. Food Sci., 31: 55–65. Glucosamine and chondroitin sulfate, components of normal cartilage, are used as ingredients in dietary supplements intended to treat osteoarthritis and/or to support joint health. Of concern is the documented lack of quality in many ...

Dietary supplements: red wine, ortolans, and chondroitin sulfate.

Zonal distribution of chondroitin-4-sulphate/dermatan sulphate and chondroitin-6-sulphate in normal and diseased human synovium.

OBJECTIVES Chondroitin sulphate is the major sulphated glycosaminoglycan present in the extracellular matrix of soft connective tissues and the aim of this study was to investigate the distribution of chondroitin sulphate species in normal and diseased synovium. METHODS Distribution of chondroitin-4-sulphate/dermatan sulphate (Ch4S/DS) and chondroitin-6-sulphate in normal (n = 6), osteoarthri...

Nature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen.

The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate-proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroi...

Quality Certification Programs for Dietary Supplements.

This article was written by Sharon R. Akabas, PhD, director of the Master of Science in nutrition and associate director for educational initiatives, Columbia University, Institute of Human Nutrition, New York, NY; Gretchen Vannice, MS, RDN, consultant, Applied Nutrition Consulting, Santa Cruz, CA; John B. Atwater, PhD, senior director, USP Verification Programs, United States Pharmacopeial Con...